Studies

Double blind randomized controlled trial  of patients who had Achilles tendinopathy (AT) for at least 3 months. Two different exercise regimes were compared, with and without the addition of photobiomodulation (PBM) therapy. Study conclusions were that twice daily exercise sessions were not necessary; equivalent results were obtained with two exercise sessions per week. Benefit was observed with the addition of PBM. Final VISA-A scores with 2 exercise sessions/week and PBM therapy were 99 out of 100. Download

Studies

A rat model of induced tendonitis was used to evaluate the effect of laser therapy on inflammatory signaling. The laser group had significantly lower mRNA for IL-6, COX-2 and TGF-β than control animals in both acute and chronic phases. Laser therapy significantly reduced mRNA TNF-α only at the chronic phase. Laser therapy is effective for the reduction of mRNA expression for pro-inflammatory mediators. Study Title: Low-level laser therapy (LLLT; 780 nm) acts differently on mRNA expression of anti- and pro-inflammatory mediators in an experimental model of collagenase-induced tendinitis in rat

Studies

Two case studies are presented that demonstrate the potential effectiveness of laser therapy applied transcranially to the forehead and scalp for the treatment of traumatic brain injury (TBI).

Studies

Fifteen patients with documented chronic tendinosis of the elbow were randomized into sham or laser therapy treatment. Multiple pain measures, handgrip strength and functional impairment all improved with respect to sham treatment. Statistical significance was maintained to one-year follow-up. Download

Studies

Book chapter on the advances in laser therapy as a therapeutic modality.

Studies

In this study, women with fibromyalgia syndrome were randomized to receive laser therapy treatment or sham heat gun treatment. Treatments were administered twice a week for 4 weeks at eight tender points across the neck, shoulders and back. Laser therapy treatment significantly improved upper body flexibility, fibromyalgia impact score and a composite measure of pain compared to the sham treatment. Download

Studies

This study evaluated HILT (High Intensity Laser Therapy) alone or with exercise for treatment of chronic low back pain. The HILT was pulsed Nd:Yag (1,064 nm) delivered a dose of 3,000 J. Results indicate that HILT combined with exercise was more effective than either HILT alone or placebo + exercise.

Studies

Treated C2 C12 murine skeletal muscle cells with different laser doses and measured the activation of AMPK and p38 (mitochondrial biogenesis signaling molecules). They found an optimal activation of these molecules and applied optimal treatment dose over a period of 4 consecutive days. They believe that their study shows that the laser light is capable of altering mitochondrial signaling and regulatory proteins in skeletal muscle tissue without cardiovascular and/or inflammatory influence. Download

Studies

Case Report–Girl with spinal cord stroke LiteCure laser was used as part of successful multimodal physical therapy approach to help restore gait.

Studies

Pilot study consisting of ten patients with at least one month of myofascial pain. Patients underwent two weeks of class IV laser treatment. A majority of the patients who underwent laser therapy showed improvement in pain assessment at 25 and 30 days post treatment. This study warrants a larger, controlled clinical study.